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Hey Rhesus, What’s Your Type?

For most people, knowing their blood type is about as relevant to their day to day lives as knowing the capital of Chad (N'Djamena).  Yet, with blood it is a difference between life and death so we had to ask, what is up with blood types, and why do they matter?

Although you can’t judge a book by its cover, you can judge a red blood cell by its surface.  The ABO blood typing system works by identifying which (if any) antigens (microscopic protein markers) you have on your red blood cells.  The A antigens make for type A blood.  B antigens make for type B.  Both A and B make for AB blood, and neither A nor B makes for type O (which you can think of as a zero since it means that the red blood cell has neither of the antigens).  So everyone in the world falls into one of the four categories: A, B, AB, or O.

Then to the letter you have to add a plus or minus sign to indicate the Rhesus or Rh factor, which was named after the monkeys being studied when they found yet another antigen (marker) which only some people possess (actually over 80%).  This time there is only one antigen so if you have it you are positive (+) and if you don’t you are negative (-). 

Blood Type

Percentage in the U.S. Population

O +

38

A +

34

B +

9

O -

7

A -

6

AB +

3

B -

2

AB -

1

Simple enough right?  Blood type is just a letter and a sign, but why do we need to know that?  The answer is because if you receive the wrong type of blood it could be fatal.  The only blood type that can be given to everyone (the universal donor) is O negative, and as you can see above, it is relatively rare.  The rest of the blood types vary in how fussy they are about mixing with other blood types. 

Of course there is more to your blood than just red blood cells (platelets and white blood cells primarily), but at least now you know why blood type does matter.  

Did you know you could make a career out of studying blood?  Hematologists are doctors who study diseases of the blood - you might want to check it out.